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WHO Rapid Alert System


Alert 4/2016 : Falsified Quinine Sulphate circulating in West and Central Africa - 11/11/2016

This Medical Product Alert relates to the recent circulation of two confirmed falsified versions of Quinine Sulphate circulating in Cameroon and the Democratic Republic of the Congo, containing zero active pharmaceutical ingredient. These products were initially discovered by a local NGO. They initially failed field screening and were submitted to a WHO pre-qualified Quality Assurance laboratory. Subsequent analysis showed that neither product contained any of the stated active pharmaceutical ingredient.  Details and photographs of the product are shown in the Alert



Medical Product Alert N° 4/2016. Falsified Quinine Sulphate in West and Central Africa : Medical Product Alert N° 4/2016. Falsified Quinine Sulphate in West and Central Africa - 8/19/2016

This Medical Product Alert relates to the recent circulation of two confirmed falsified versions of Quinine Sulphate circulating in Cameroon and the Democratic Republic of the Congo, containing zero active pharmaceutical ingredient.

Quinine Sulphate is used for the treatment of Falciparum Malaria in the region.

These products were initially discovered by a local NGO. They initially failed field screening and were submitted to a WHO pre-qualified Quality Assurance laboratory. Subsequent analysis showed that neither product contained any of the stated active pharmaceutical ingredient.



Alert 3/2016 : Falsified Hepatitis C medicines circulating in South East Asia - 2/25/2016

 This Medical Product Alert relates to the circulation of confirmed falsified versions of Sofosbuvir 400mg + Ledipasvir 90mg and Daclatasvir 60mg in South East Asia.  Both products are used to treat Hepatitis C. Daclatasvir 30mg and the fixed dose combination of Sofosbuvir 400mg + Ledipasvir 90mg are on the WHO list of Essential Medicines.



Alert 2/2016 : Falsified AMARIL yellow fever vaccines circulating in South East Asia - 2/11/2016

This Medical Product Alert relates to the confirmed circulation of falsified versions of 'AMARIL stabilised vaccine' in South East Asia.    This vaccine is used to immunise against yellow fever and is a WHO prequalified product. Yellow fever vaccine is on the WHO list of Essential Medicines.



Alert 1/2016 : Falsified phenobarbitone tablets circulating in West Africa - 2/5/2016

This Medical Product Alert relates to the circulation of falsified versions of phenobarbitone (also known as phenobarbital) in West Africa. Phenobarbital is used as a treatment against epilepsy and is frequently dispensed free of charge in community-care health centres.



Alert 5.2015 : Falsified Emergency Contraceptive circulating in East Africa - 11/18/2015

This Medical Product Alert relates to the confirmed circulation of falsified versions of Postinor-2
(Levonorgestrel) in East Africa.
Postinor-2 is a widely used emergency contraceptive that should contain 0.75mg of levonorgestrel.
The genuine product is manufactured by Gedeon Richter.
In August 2015, the Uganda National Drug Authority notified WHO of the seizure of falsified
Postinor-2 discovered in Kampala, Uganda. All packs reported bear the same batch number and
expiry/manufacturing dates. Please read the attached document for more information.

Alert 4/2015 : Adverse reactions caused by Falsified Diazepam in Central Africa - 7/6/2015

This Medical Product Alert relates to the confirmed circulation of falsified versions of Diazepam
tablets circulating in Central Africa.


Since December 2014, over 400 patients in the north east region of the Democratic Republic of Congo
(DRC) have suffered from an acute dystonic reaction affecting the muscles of the face, neck and
tongue. This reaction usually lasts, without treatment, for between 3 to 4 days, sometimes re-occurs,
and has resulted in up to 40 hospital admissions per week. A detailed investigation carried out in DRC
has revealed that patients had been taking Diazepam to treat a wide range of illnesses.

Please read the attached document for more information.

Alert 3/2015 : Falsified Meningitis Vaccines circulating in West Africa UPDATE - 5/27/2015

This Medical Product Alert relates to the confirmed circulation of falsified versions of Meningitis
Vaccines in Niger and follows Medical Product Alert 2/2015 issued on the 22nd May 2015.

This alert is about the Menomune product, which is genuinely produced by Sanofi Pasteur. Please read the attached document for more information.

Alert 2/2015 : Falsified Meningitis Vaccines circulating in West Africa - 5/22/2015

This Medical Product Alert relates to the confirmed circulation of falsified versions of Meningitis
Vaccines in Niger.

WHO has just launched a rapid alert concerning  batches of  Mencevax circulating in Niger. The genuine meningitis vaccine is manufactured by GlaxoSmithKline (GSK). The falsified batches showed inconsistencies in the packaging material, batch numbers, manufacturing/expiry dates confirmed by GSK. Please refer to the attached WHO document for more information.

Alert 132 : Falsified Medicines West and Central Africa - 10/13/2014

This Drug alert is in follow up to Drug Alert 131 regarding falsified antimalarial products in
circulation in West and Central Africa. Six (6) new falsified medical products (antimalarials and
antibiotic) have been discovered in Niger in September 2014.

Alert 131 : Falsified antimalarial medicines in west and central Africa - 3/25/2014

This drug alert concerns three separate falsified antimalarial medicines discovered in Cameroon,
Ghana and Liberia.

Alert 130 : Falsified batches of Coartem recently circulating in Cameroon - 11/8/2013

This drug alert serves as an update to WHO Drug Alert No. 127 of 3 May 2013 concerning falsified
batches of Coartem that were circulating in Western and Central Africa.

Alert 129 : Contaminated Dextromethorphan active pharmaceutical ingredient - 10/17/2013

Full laboratory testing of the Dextromethorphan showed that it was contaminated with Levomethorphan,
the enantiomer of Dextromethorphan, which is a potent opioid analgesic internationally controlled under
schedule 1 of the single convention on Narcotic Drugs 1961.

Alert 127 : Falsified batches of Coartem recently circulating in Western and Central Africa - 5/3/2013

In early 2013 a batch of falsified Coartem was discovered in Yaoundé, Cameroon, containing no active pharmaceutical ingredients.

Alert 126 : Contaminated Dextromethorpan Active Pharmaceutical Ingredient - 1/24/2013

On the 23rd November 2012, a serious incident occurred in Lahore, Pakistan which resulted in the death
of approximately 20 persons and a number of other serious adverse reactions. All of those affected had
consumed a cough syrup with the brand name Tyno, 120ml, locally produced by Reko Pharmacal with
Dextromethorphan as the principal active pharmaceutical ingredient.